An introduction to large-scale methods in Biosciences

22 Setembro 2021, 13:30 • Margarida Henriques da Gama Carvalho

1. Define the term 'omics' and provide some examples of 'omics' approaches;
2. Contextualize these research approaches in the current landscape of BioSciences and its aims; 
3. Understand the evolution from biochemistry/molecular biology to the systems biology level and the potential of ensuing applications;
4. Understand the importance and need for quantitative and large-scale data analysis approaches in the current panorama of biological sciences and the need for a new generation of 'Bio-professionals';
5. Understand the difference between data and knowledge. 
6. Acquire an historical perspective for the appearance of 'Big Science' and 'Omics' Technologies;
7. Have an in-depth understanding of the aims and achievements of the Human Genome Project;
8. Understand the impact of the HGP in technological development in the 20th century;
9. Review and understand the basic principles of conventional DNA sequencing (Sanger sequencing)
10. Identify and explain microarrays and their different applications as the first true 'omics' technology.