RNA metabolism in neurodegeneration II

9 Novembro 2022, 12:00 • Margarida Henriques da Gama Carvalho

RNA metabolism in neurodegeneration II - Spinal Muscular Atrophy

9 Novembro 2022, 10:00 • Margarida Henriques da Gama Carvalho

RNA metabolism and neurodegeneration – connections and functional significance

Making sense of multiple disease genes – common phenotypes – diseases as molecular network disfunctions

The special case of Spinal Muscular Atrophy (SMA) and its links to ALS

RNA metabolism in neurodegeneration I – ALS/FTD

2 Novembro 2022, 12:00 • Margarida Henriques da Gama Carvalho

Review of last weeks concepts

RNA metabolism in ND I

2 Novembro 2022, 10:00 • Margarida Henriques da Gama Carvalho

ALS & FTD

Main characteristics of ALS – symptoms, presentation, genetics

Neuropathology of ALS – a protein aggregation disease?

Structural characteristics of ALS-associated proteins – Prion like domains as a theme

Genetics in ND

19 Outubro 2022, 12:00 • Margarida Henriques da Gama Carvalho

Correlation and Causation in Science - a critical reflection on the evidence for aggregates as the cause for neurodegeneration

What is the role of genetics in Neurodegeneration?