Animal and Cellular Models in Neurodegeneration

9 Outubro 2024, 12:00 • Cláudio Emanuel Moreira Gomes

Experimental models in neurodegeneration: the importance of in vitro, ex vivo, and in vivo models. Evolving Therapies in NDD: Research and discovery.

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Molecular Basis of Alzheimer’s Disease

9 Outubro 2024, 10:00 • Cláudio Emanuel Moreira Gomes

Alzheimer’s Disease: characteristics and risk factors; molecular aspects of amyloid-beta and Tau proteins, neurobiology, and formation/spread of toxic aggregates. APP, secretases, and presenilins. Cellular processes in AD pathogenesis. Structural biology of Alzheimer’s Disease. Familial AD and the amyloid cascade hypothesis.

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Optogenetics methods in Neuroscience

2 Outubro 2024, 12:00 • Cláudio Emanuel Moreira Gomes

Neuroscience and the brain (continued) | Advanced methods for studying the nervous system using optogenetics and examples of research.

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Neurobiology of the Brain

2 Outubro 2024, 10:00 • Cláudio Emanuel Moreira Gomes

The brain: anatomy and cells, introduction to neurobiology. Fundamentals of neuroscience. Invited Lecture: Dr. Joaquim Silva, MD, PhD (Champalimaud Foundation).

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Protein aggregation and amyloid state in neurodegeneration

25 Setembro 2024, 12:00 • Cláudio Emanuel Moreira Gomes

Mmechanisms of amyloid formation, amyloid structure, cellular protein deposits, protein aggregation propensity, detection methods, and structural approaches for studying amyloids. Aggregation kinetics and mechanisms. Evolving Therapies in NDD: Research and discovery.

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