Overview and example of Evolutionary Medicine

8 Janeiro 2020, 14:00 • Patricia Beldade

Overview of Evolutionary Medicine. How it differs from clinical genetics. Disease symptoms as unhealthy phenotypes. Methods from evolutionary biology (phylogenetic analysis, comparative method) used to address medically important problems. Realization of range of variation in pathology. Evolution and cancer. Hallmarks of cancer and relationship to evolution of multicellularity. Transmissable tumours in dogs and Tansmanian devils. Moving away from single therapy. Curing versus managing disease. Discussion led by invited professor Thiago Lopes Carvalho (Champalimaud).