Prediction of protein families and domains

3 Outubro 2022, 11:00 • António Eduardo do Nascimento Ferreira

Demonstration of the application of deterministic patterns on the sequence of a protein using too PROSITE. Classification of proteins into families and the detection of domains from sequences. Multiple sequence alignments as the starting procedure in the classification of new proteins. Position Specific Scoring Matrices and Hidden Markov models as methods of feature prediction from sequences. The assessment of the performance of methods. The InterPro portal as an aggregative tool for family/domain prediction from sequence. Demonstration of the use of InterPro in a multi-domain protein.