Tema 3: Introduction to GWAS: A hands-on tutorial.

3 Novembro 2021, 16:00 • Ana Filipa Gonçalves Milhinhos

1. Introduction to GWAS. 1.1. Motivation for performing GWAS. 1.2. Genetic variation background. 1.3. Why plants (A. thaliana)? 1.4. Linkage Disequilibrium. 1.5. Population Structure. 2. GWAS methods overview (Linear model, Non-parametric test, Linear Mixed Model, Advanced Linear Mixed Models). 2.1. Caveats & Problems. 3.Introduction to GWA-Portal. Hands-on tutorial (GWA-Portal). 2.1. Create a GWAS study.  3.2. Analyse Manhattan plots. 3.3. LD plots & Detailed SNP analysis.