Multivalency, biochemical engineering and infection

9 Dezembro 2016, 14:00 • Amélia Pilar Grases dos Santos Silva Rauter

Multivalency and glycocalix. Sialyl-Lewis X fiunctional groups essential to protein binding. Glycomimetics. Glycodendrimers, glycoclusters and other mimetics. Manipulation of glycocalix structures – biochemical engineering. Glycobiology and infection - microbial adhesion. The role of pili for host invasion. The lectin FimH, its carbohydrate recognition domain and the development of inhibitors.