Modulo 2 Microbiologia Humana: Interações hospedeiro patogeno e mecanismos de imunidade inata
28 Fevereiro 2023, 14:00 • Elsa Anes
Modulo 2 Microbiologia humana: interações hospedeiro patogeno e mecanismos de imunidade inata
Innate Immunity:
a common end for different strategies
1 The innate immunity inducers and sensors: PAMPS, DAMPS and soluble receptors-Complement; integral protein receptors-TLRs, cytosolic receptors.
2 TLR signalling in the epithelia and mucosae.
3 Mediators and effectors of innate immunity sensors: cells and secretion of antimicrobial peptides, pro inflammatory cytokines, IFNγ, phagolysosome fusion, oxidative burst, TNFα, IL1β, type I interferons,
4 Cytosolic receptors for sensing intracellular pathogens: NLRs and the inflammasome,RNA sensors, DNA sensors, the sequestosome.
5 Cell autonomous immunity