Enzyme-linked Receptors (II)
22 Maio 2018, 17:00 • Paulo Henrique Carrasquinho de Matos
• Activation of RTK effector molecules
• Activation of Ras downstream of RTKs
• The Ras-RAF-MEK-ERK MAP kinase cascade
• Signaling dynamics through Crosstalk
• Dynamics of ERK activity - transient versus sustained activation
• MAPK cascade mutations in cancer