Enzyme-linked Receptors (II)

23 Maio 2017, 17:00 • Paulo Henrique Carrasquinho de Matos

•       Activation of RTK effector molecules

•        Activation of Ras downstream of RTKs

•        The Ras-RAF-MEK-ERK MAP kinase cascade

•        Signaling dynamics through Crosstalk

•        Dynamics of ERK activity - transient versus sustained activation

•        MAPK cascade mutations in cancer