9ª Aula

14 Novembro 2019, 17:30 • Maria Salomé Esteves Cabral

7. Statistical Analysis of RCT. Parallel Group Design. Two Groups. >2 Groups

7.2.4  Inference

Example 7.2.1 (cont) and Example 7.2.2 (cont)

7.2.5  Prognostic Factors

9ª Aula

14 Novembro 2019, 16:00 • Maria Salomé Esteves Cabral

7. Statistical Analysis of RCT. Parallel Group Design. Two Groups. >2 Groups

7.2.3  Interpretation of Model Parameters.

One binary exploratory variable.

 Exercises 5:1 (Example 7.2.1)

One continuous exploratory variable.

One exploratory variable with k>2 classses

Exercises 5:2 (Example 7.2.2)

8ª Aula

7 Novembro 2019, 17:30 • Maria Salomé Esteves Cabral

7. Statistical Analysis of RCT. Parallel Group Design. Two Groups. >2 Groups

7.1.6  Kruskall-Wallis

Example 7.1.4

Home-Work-Exercises 4:  3

7. Statistical Analysis of RCT. Parallel Group Design. Two Groups. >2 Groups

7.2      Binary Data

7.2.1   Generalized Linear Model

8ª Aula

7 Novembro 2019, 16:00 • Maria Salomé Esteves Cabral

7. Statistical Analysis of RCT. Parallel Group Design. Two Groups. >2 Groups

Example 7.1.1 (Exercises 4:1).

7.1.2 Multiple Comparations

Example 7.1.1 (cont)  (Exercises 4:2).

7.1.3  Model Adequacy Checking

Example 7.1.1 (cont)  

7.1.4  Power of the Test

7.1.5 Sample size determination and the minimum detectable difference

Example 7.1.2, Example 7.1.1 (cont)  and Example 7.1.3

7ª Aula

31 Outubro 2019, 17:30 • Maria Salomé Esteves Cabral

R package 

The use of binom.test, mcnemar.test and dimMcNemar functions

Exercises 3:  4 and 5

7. Statistical Analysis of RCT. Parallel Group Design. Two Groups. >2 Groups

7.1     Models for Continuous Endpoints