4ª Aula

10 Outubro 2019, 17:30 • Maria Salomé Esteves Cabral

Exercises 2

Resolution of exercises 1, 2 and 3.

5. Statistical Analysis of RCT. Parallel Group Design. Two Groups

5.1     Continuous data.

5.1.1   The Behrens-Fisher problem and the t-Test.

4ª Aula

10 Outubro 2019, 16:00 • Maria Salomé Esteves Cabral

4. Introduction to Statistical Analysis of CT

4.1 Graphical Representation

4.2 Hypothesis Tests

4.3 Confidence Intervals

4.4 Statistical analysis of parallel and controlled trials. General Considerations

3ª Aula

3 Outubro 2019, 17:30 • Maria Salomé Esteves Cabral

3. Trial Designs & Other Studies

3.1 Parallel Group Designs

3.2 In Series Designs

3.3 Crossover Designs

3.4 Sequential Designs

3.5 Factorial Designs

3.6 Cohort Studies

3.7 Case-Contolo Studies

3.8 Case Series and Case Reports

3.9 Internal Validity vs External Validity.

3ª Aula

3 Outubro 2019, 16:00 • Maria Salomé Esteves Cabral

2. Randomization

2.5 Minimization.

2.6 Randomization Software.

Examples.

Exercises 1: 1C; 3; 4.

2ª Aula

25 Setembro 2019, 17:30 • Maria Salomé Esteves Cabral

1. Basic Concepts in Clinical Trials (CT)

1.5 Protocol

1.6 Historical Background

Exercises 1: 1A; 1B

2.Randomization

2.1 Why randomization?

2.2 Simple Randomization.

2.3 Restricted Randomization-Blocking

Examples

Home-work: Exercises 1: 1C.