Intracellular protein degradation/Folding and human disease

15 Dezembro 2025, 11:00 • Carlos Miguel Ribeiro da Silva Farinha

Intracellular protein degradation

§   The lysosome

§   Autophagy

§   Protein ubiquitination

§   The proteasome: structure and mechanism of action

§   Ubiquitin-like proteins and protein sumoylation

 

Folding and human disease

§  Misfolding and aggregation

§  Aggregation, aging and life-style

§  Misfolded proteins as infectious agents

§  Folding, UPR and cancer

§  Misfolding and dysfunction by absence

§  Cystic Fibrosis – CFTR Folding and Trafficking 

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Apresentação dos artigos 3.3. e 3.4.

15 Dezembro 2025, 09:30 • Carlos Miguel Ribeiro da Silva Farinha

Apresentação dos artigos 3.3. e 3.4.

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Discussão de artigos.

15 Dezembro 2025, 09:30 • Bárbara Joana de Almeida Henriques

Discussão de artigos.

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Intracellular Protein Trafficking

24 Novembro 2025, 11:00 • Carlos Miguel Ribeiro da Silva Farinha

Intracellular Protein Trafficking

§   The Secretory Pathway

§   Traffic between different compartments

§   Signal sequences and patches

§   Transport vesicles - fusion

§   SNARE and Rab proteins

§   Endocytosis

§   Exocytosis

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Apresentação dos artigos 3.3. e 3.4.

24 Novembro 2025, 09:30 • Carlos Miguel Ribeiro da Silva Farinha

Apresentação dos artigos 3.3. e 3.4. 

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