Dendritic cells

31 Outubro 2018, 15:00 • Maria Margarida Blasques Telhada

Dendritic cells. The DC subsets. Conventional DCs. Plasmacytoid dendritic cells. Epidermal Langerhans cells. Stages and transcription factors for DC development. Macrophages, IRF8⁺, IRF4⁺ and Langerhans cells in mouse tissues. Correspondence between murine and human DC subsets. Functions of dendritic cell subsets in the immune response. Functions of cDC1 in the immune response. Dendritic cell subsets serve distinct immune effector modules. Intestinal dendritic cells. Dendritic cell subsets in the mouse and human intestinal lamina propria. Murine intestinal CD103⁺ CD11b^- cDC. Murine intestinal CD103⁺ CD11b⁺  cDCs. Murine intestinal CD103^- CD11b⁺  cDCs. Functions of intestinal dendritic cell subsets. Functions of DC in homeostasis – resident T cells formation. Functions of DC in homeostasis -  iTreg and oral tolerance induction. cDC functions in the small intestine LP. cDC functions in the intestinal lymph nodes.