Primary immunodeficiencies.

6 Dezembro 2018, 14:00 • Maria Margarida Blasques Telhada

Primary immunodeficiencies. Primary immunodeficiencies due to defects in innate immune responses: type 1 leukocyte adhesion deficiency, Chronic granulomatous disease, defects of the IFNg / IL-12 axis, complement deficiencies. Primary immunodeficiencies due to defects in adaptive immune responses. Severe combined immunodeficiencies: - #X linked SCID, SCID Jak3, SCID IL-7Ra, SCID CD45, immunodeficiencies-ADA and PNP defects, SCID RAG, Omnen syndrome, SCID artemis, reticular dysgenesis. Combined immunodeficiencies: MHC expression deficiencies. T-cell specific immunodeficiencies: Defects in TCR signaling. Deficiencies in antibody production. #X-linked agammaglobulinemia (XLA) or Bruton. Agammaglobulinemia non Bruton. Defects in B-cell activation. Selective IgA deficiency. Hyper IgM syndromes.