Transplantation immunology.

5 Dezembro 2018, 15:00 • Maria Margarida Blasques Telhada

Transplantation immunology. Graft rejection occurs based on immunologic principles. T cells are essential for transplant rejection. Molecular bases of allorecognition. Immune recognition of allogeneic MHC molecules. Immunology of solid organ transplants. Minor histocompatibility antigens (MiHA). Examples of minor histocompatibility murine and human antigens. Types of clinical rejection and its mechanisms: hyperacute rejection, acute rejection and chronic rejection. Graft-versus-host disease. Transplantation immunology – therapy generalized immunosuppressive therapy, specific immunosuppressive therapy.