Lecture 4: Innate Immunity: a common end for different strategies (first part)
16 Março 2020, 17:00 • Elsa Anes
Innate Immunity:
a common end for different strategies (first part)
1 The innate immunity inducers and sensors: MAMPS, DAMPS and soluble receptors-Complement; integral protein receptors-TLRs, cytosolic receptors.
2 TLR signalling in the epithelia and mucosae.
3 Mediators and effectors of innate immunity sensors: cells and secretion of antimicrobial peptides, pro inflammatory cytokines, IFNγ, phagolysosome fusion, oxidative burst, TNFα, IL1β, type I interferons,
4 Cytosolic receptors for sensing intracellular pathogens: NLRs and the inflammasome,RNA sensors, DNA sensors, the sequestosome.
5 Programmed cell death and innate immunity