Sumários
Synthesis of 2-amino-5-iodopyridine.
16 Novembro 2016, 16:00 • Christopher David Maycock
Selective iodination of 2-aminopyridine in the 5-position using iodine in acetic acid.
Synthesis of Carpanone (Chapman)
16 Novembro 2016, 14:00 • Christopher David Maycock
Claisen rearrangement of phenyl allyl ethers to form C-allyl compounds. Similar to Cope rearrangement with the all C analogues.
Continuation of listed block 1 experiments.
9 Novembro 2016, 16:00 • Christopher David Maycock
See previous summary for list
Dithioacetals and isocyanates
9 Novembro 2016, 14:00 • Christopher David Maycock
Methods for the synthesis of dithioacetals. Comparison with O-acetals and O.S-acetals. Methods for the regeneration of the corresponding carbonyl compounds. Dithianes a special case. Formation of organometallics and their reactions, alkylation, acylation, hydroxyalkylation. Formation of aldehydes and ketones from. Rearrangement of acyl azides and the formation of isocyanates. Reactions of isocyanates to form ureas and carbamates. Use of chiral isocyanates for the resolution of racemic alcohols.
Continuation of block 1 experiments.
2 Novembro 2016, 16:00 • Christopher David Maycock
See previous summaries for experiments.