Apresentação dos artigos 3.3. e 3.4. Carlos Farinha

5 Dezembro 2022, 09:30 • Carlos Miguel Ribeiro da Silva Farinha

Apresentação dos artigos 3.3. e 3.4. 

Folding in the endoplasmic reticulum/Posttranslational modifications (PTMs) in proteins

28 Novembro 2022, 11:00 • Carlos Miguel Ribeiro da Silva Farinha

Folding in the endoplasmic reticulum

§  Signal Sequence

§   Translocon

§   Signal Peptidase

§   Post-translational translocation

§   Membrane proteins

§   Prediction of membrane protein topology

§   Unfolded Protein Response (UPR)

§   ER Associated Degradation (ERAD)

Posttranslational modifications (PTMs) in proteins

§   Role of PTMs

§   Types of PTMs

§   Protein glycosylation in the ER

§   Glycosylation, folding and ER quality control

Dicussion of papers

28 Novembro 2022, 09:30 • António Eduardo do Nascimento Ferreira

Dicussion of papers.

Apresentação dos artigos 3.1. e 3.2.

28 Novembro 2022, 09:30 • Carlos Miguel Ribeiro da Silva Farinha

Apresentação dos artigos 3.1. e 3.2. 

Proteostasis and folding in vivo/Molecular Chaperones

21 Novembro 2022, 11:00 • Carlos Miguel Ribeiro da Silva Farinha

Proteostasis and folding in vivo

§  Proteostasis

§   Fundamental principles of in vivo protein folding

Molecular Chaperones

§   Molecular Chaperone - origin and definition

§   Main chaperone families

§  Mechanism and function for Hsp70 chaperones

§   Other families: chaperonines, Hsp90 and Hsp100

§   Chaperone networks in protein folding

§   Enzymes and protein folding

§   Chaperones and cellular stress