Sumários

17 Outubro 2023, 17:00 • Ines Pankonien

· Ussing chamber technique

· Analyse ion transport through CFTR, using electrophysiological method such as the Ussing chamber

· Study how mutations in CFTR ion channel affect channel activity

· Analyse the effect of pharmacological drugs in the rescue of these mutations

· Learn how we can use electrophysiology to predict the best drug for a patient with Cystic Fibrosis

17 Outubro 2023, 16:00 • Ines Pankonien

· Ussing chamber technique

· Analyse ion transport through CFTR, using electrophysiological method such as the Ussing chamber

· Study how mutations in CFTR ion channel affect channel activity

· Analyse the effect of pharmacological drugs in the rescue of these mutations

· Learn how we can use electrophysiology to predict the best drug for a patient with Cystic Fibrosis

16 Outubro 2023, 14:00 • Romana Santos

Potencial de Ação.

Patch-clamp vs voltage clamp.

Neurónios que disparam vs neurónios que não disparam.

Propagação do potencial de ação.

11 Outubro 2023, 17:00 • Ines Pankonien

Physiological roles of ion channels/transporters

Principle of membrane transport

Two types of membrane transport proteins

· Ion channels

· Ion transporters

Epithelia

Epithelial ion channels/transporters

· Focus on CFTR, ENaC, Na⁺ K⁺ pump, NKCC1

· Channelopathy: Cystic Fibrosis

· Preparation for practical class measuring ion conductance in epithelial cells using the Ussing chamber technique

11 Outubro 2023, 16:00 • Ines Pankonien