Sumários

Numerical Implementation of a Two-Variable Systems

11 Março 2026, 13:30 • Rafael Neto Henriques

This session advanced the students' technical skills in numerical simulation by transitioning from single to multiple state-variable systems. The class began with the formulation of differential equations for the given problem, followed by the step-by-step implementation of these equations using the Euler method.

General Classification of Models

11 Março 2026, 10:00 • Rafael Neto Henriques

This lecture introduces the general terminology used for model classification, distinguishing between qualitative (verbal, mental, conceptual) and quantitative models (mathematical equations). Models are further categorized based on their intended purpose as descriptive, interpretive, predictive, or explanatory. A critical distinction is established between data-driven (black-box) models, which provide input-output descriptions based on experimental data, and structural models, which explicitly represent underlying physiological mechanisms. The session concludes with an active learning exercise where students discuss the diverse applications of these models - including aiding understanding, hypothesis testing, inferential measurement, and clinical diagnosis - to determine which modeling approach is most appropriate for a specific physiological purpose.

Numerical Implementation of a Two-Variable Systems

11 Março 2026, 08:30 • Rafael Neto Henriques

Homeostatic Control Mechanisms

10 Março 2026, 11:00 • Rafael Neto Henriques

In the first part of the lecture, it was presented how the interaction between two variables can be modeled using mutual causality. In the second part of the lecture, the mechanisms that physiological systems use to ensure homeostasis at various levels were explored, ranging from modeling simple and complex enzyme reactions to the different types of hormonal control: kinetic, metabolic, and trophic hormones. The session also covered the more integrated control exerted by the nervous system. The class concluded by describing key features of physiological control that become apparent through these mechanisms: hierarchy, which organizes systems from genes to organisms, and redundancy, which provides reliability through duplicated functions. Finally, the lecture discussed the complexity of measuring function and behavior in physiological systems due to practical and ethical constraints

An application of Euler's method. Project discussion.

10 Março 2026, 08:30 • Alexandre da Rocha Freire de Andrade

An example of application of Euler's method: application to the free falling problem and extension to the single-tank proble. Discussion about paper selection for group project.